29 research outputs found

    The Community Authorization Service: Status and Future

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    Virtual organizations (VOs) are communities of resource providers and users distributed over multiple policy domains. These VOs often wish to define and enforce consistent policies in addition to the policies of their underlying domains. This is challenging, not only because of the problems in distributing the policy to the domains, but also because of the fact that those domains may each have different capabilities for enforcing the policy. The Community Authorization Service (CAS) solves this problem by allowing resource providers to delegate some policy authority to the VO while maintaining ultimate control over their resources. In this paper we describe CAS and our past and current implementations of CAS, and we discuss our plans for CAS-related research.Comment: Talk from the 2003 Computing in High Energy and Nuclear Physics (CHEP03), La Jolla, Ca, USA, March 2003. 9 Pages, PD

    A Web-based and Grid-enabled dChip version for the analysis of large sets of gene expression data

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    <p>Abstract</p> <p>Background</p> <p>Microarray techniques are one of the main methods used to investigate thousands of gene expression profiles for enlightening complex biological processes responsible for serious diseases, with a great scientific impact and a wide application area. Several standalone applications had been developed in order to analyze microarray data. Two of the most known free analysis software packages are the R-based Bioconductor and dChip. The part of dChip software concerning the calculation and the analysis of gene expression has been modified to permit its execution on both cluster environments (supercomputers) and Grid infrastructures (distributed computing).</p> <p>This work is not aimed at replacing existing tools, but it provides researchers with a method to analyze large datasets without any hardware or software constraints.</p> <p>Results</p> <p>An application able to perform the computation and the analysis of gene expression on large datasets has been developed using algorithms provided by dChip. Different tests have been carried out in order to validate the results and to compare the performances obtained on different infrastructures. Validation tests have been performed using a small dataset related to the comparison of HUVEC (Human Umbilical Vein Endothelial Cells) and Fibroblasts, derived from same donors, treated with IFN-α.</p> <p>Moreover performance tests have been executed just to compare performances on different environments using a large dataset including about 1000 samples related to Breast Cancer patients.</p> <p>Conclusion</p> <p>A Grid-enabled software application for the analysis of large Microarray datasets has been proposed. DChip software has been ported on Linux platform and modified, using appropriate parallelization strategies, to permit its execution on both cluster environments and Grid infrastructures. The added value provided by the use of Grid technologies is the possibility to exploit both computational and data Grid infrastructures to analyze large datasets of distributed data. The software has been validated and performances on cluster and Grid environments have been compared obtaining quite good scalability results.</p

    The Nexus Task-parallel Runtime System

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    A runtime system provides a parallel language compiler with an interface to the low-level facilities required to support interaction between concurrently executing program components. Nexus is a portable runtime system for task-parallel programming languages. Distinguishing features of Nexus include its support for multiple threads of control, dynamic processor acquisition, dynamic address space creation, a global memory model via interprocessor references, and asynchronous events. In addition, it supports heterogeneity at multiple levels, allowing a single computation to utilize different programming languages, executables, processors, and network protocols. Nexus is currently being used as a compiler target for two task-parallel languages: Fortran M and Compositional C++ . In this paper, we present the Nexus design, outline techniques used to implement Nexus on parallel computers, show how it is used in compilers, and compare its performance with that of another runtime system. 1 Int..

    Spaceflight Operations Services Grid Prototype

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